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Wednesday, August 26, 2020
Curriculum Vitae Essay Example | Topics and Well Written Essays - 500 words
Educational plan Vitae - Essay Example You ought to have strong system and Server bolster aptitudes prevalently in the 2k/2k3 field. You ought to head towards the MCSA/MCSE or if nothing else have the significant degree of expertise to complete every day obligations (The capability itself isn't vital in spite of the fact that would be valuable). You will likewise require solid abilities in systems administration conventions, Citrix, Active Directory and Exchange 2000/2003. On the off chance that you have understanding of against infection/byware/reinforcement (Veritas) and/or Cisco Routers and Switches it is invaluable to your application. You will be a dedicated, have an enthusiasm to succeed and a complete it disposition. This position will help build up your ranges of abilities and advance your profession in the long haul as the firm is a settled, monetarily effective undertaking. Send me your CV now. Save Time Interests: My most loved past time would be sports especially watching Football. I appreciate staying in shape and am a standard guest at my neighborhood exercise center. I additionally attempt to travel be that as it may; I have just had the chance to visit the Asian sub-landmass and North America so far. I am a legit, reliable, dedicated person who can adjust to any condition and procure the aptitudes important to guarantee this. A dependable individual with the capacity to take part in detail arranging and have great hierarchical aptitudes.
Saturday, August 22, 2020
Personal Statement Nonverbal Communication Essay Example For Students
Individual Statement : Nonverbal Communication Essay Nonverbal Communication People have the weirdest outward appearance or utilize odd motions while theyââ¬â¢re talking now and again. It makes you wonder why they are moving the manner in which they are or what is experiencing their brain to put that look all over. Understanding others messages and signals just as conveying your own messages and signals is nonverbal correspondence. In the book Communication in Everyday Life Steve Duck and David T. McMahan characterize nonverbal correspondence as ââ¬Å"any emblematic action that imparts a message other than words. â⬠1* We canââ¬â¢t help yet to think about what representative exercises mean and what messages you are conveying nonverbally also. We will first we return to where we took in these various exercises and approaches to convey without words; which returns to whoever raised us. Growing up for me was with my mom and father and my sister who was five years more seasoned than me, so in addition to the fact that I learned from my folks I took in a great deal from my sister also. With regards to my folks, my mom has all the outward appearances and not the same number of physical signals or developments in her nonverbal correspondence. The motion I recall generally growing up was her folding her arms, she utilized this as a ââ¬Å"wallâ⬠or a sign saying she was cutting off herself or didnââ¬â¢t need to be annoyed. In any case, my dad is the inverse; he will be increasingly dynamic with what he is stating and give numerous signals and developments rather than outward appearanc es. He is additionally a genuine case of how much verbal and nonverbal correspondence interconnect; which the two interconnect from multiple points of view. In my fatherââ¬â¢s model he rehashes his verbal correspondence with his nonverbal correspondence as the two compare with one another 2*. For a superior model, when he . .es that you need to make sense of on the off chance that somebody is lying or being straightforward, are the cheerful or pitiful, or what is new with them when all is said in done that the individual isnââ¬â¢t letting you know verbally. Nonverbal openness is of the utmost importance in these circumstances on the grounds that multiple occasions it can give you more data than somebody is eager to give you verbally. However, you need to realize how to comprehend the nonverbal messages being spoken with you. Signals, outward appearances, manner of speaking, and so forth would all be able to assist you with making sense of various touchy triggers that individuals have and what makes them apprehensive, cheerful, or upset. This correspondence can offer you responses that youââ¬â¢re searching for however the individual speaking with you isnââ¬â¢t really giving you the data straight up, or it can assist you with knowing what course you have to go with the discussion to find the solutions and data you are searching for.
Wednesday, August 19, 2020
Essay on Unemployment in Dubai
Essay on Unemployment in Dubai Unemployment in Dubai Dec 20, 2018 in Economics Introduction Unemployment is a major social and economic problem which is affecting both the developing and developed countries. Having information about the employment and unemployment rates of a country helps a lot in putting in place methods and policies which help sustain the economy by curbing the rate of employment. The economy of the United Arab Emirates is mainly sustained by oil, and most of the employment opportunities are found in the oil industry and related sectors such as finance and infrastructure (Muwia, 2004). Unemployment rate is defined as the number of people who are able and willing to work, but cannot find job opportunities, divided by the number of families in that selected region. Employment, on the other hand, is defined as the number of people who are actively employed.
Sunday, May 24, 2020
Lee Iacocc An American Business Leader - 1540 Words
Abstract Lee Iacocca is a businessman in the American automobile industry. He progressed up the ranks at Ford Motor Company to ultimately become its president in 1970. He is credited with such automotive hits as the Mustang and the Lincoln Mark III. He was fired by Henry Ford in 1978 due to personal differences. Chrysler Corporation was in a state of near bankruptcy in 1979 and called upon the leadership and expertise of Lee Iacocca to help save the company. Through his toughness and perseverance, he saves the Chrysler Corporation and in the process, millions of American jobs. Brian Watkins Alyssa Foskey MGMT 1115 March 29, 2015 Iacocca: An American Business Leader Lee Iacocca was born in Allentown, Pennsylvania, on October 15, 1924. His parents immigrated to America from Italy in the early 1900ââ¬â¢s in search of the American dream. Leeââ¬â¢s father was a businessman with interests in restaurants, theaters, and a car rental agency. The car rental business is what sparked Leeââ¬â¢s interest in the automobile business. Lee did well in high school and was elected president of his class in the ninth grade. After the election, he failed to stay in touch with his constituency and lost the election in the second semester. He had forgotten the importance of shaking hands and being friendly. It was one of his first lessons on leadership. Lee graduated twelfth in his high school class of over nine hundred and set his sights on pursuing engineering in college. Lee applied, and was
Wednesday, May 13, 2020
A Psychology Participant Pool Questionnaire - 1006 Words
Methods The participants in the study were racial minority undergraduates screened through a psychology participant pool questionnaire, Patient Health Questionaire-9 (PHQ-9). 100 racial minority undergraduates with elevated depression were pulled from the questionnaire. Among the 100 participants, there was 45% male and 55% female with the average age being around 19. The college undergraduates ranged from freshman to seniors with, 67% freshman, 20% Sophomores, 10% Juniors, and 3% Seniors. Among the college students, the majority were African-American at 85%, Asian 10%, and the rest 5%. If you notice the majority totals for the subcategories of the population, there was an elevated depression between African American Freshman Females. The results of the sample taken were measured based upon the PHQ-9 which screens and measures the severity of depression. There are 10 questions, that rate the frequency of the depression symptoms a person may have and gives the severity of the diagnoses overall. It is used with clinical psychology practices to understand how serious depression symptoms are, and then during treatment to understand if the methods being used are improving or worsening. The Anxiety Sensitivity Index(ASI-3) is an 18 number questionnaire used by psychologist to understand the level of anxiety sensitivity, and how to lower the rate in the individual. It is designed to improve depression and anxiety sensitivity correlated areas of the physical, cognition, andShow MoreRelatedThomas J. Dodd Research Study Sample746 Words à |à 3 Pagesundergraduate and graduate students from psychology and sociology classes at the University of Connecticut are recruited to participate in a self-report survey. A random sampl e of 240 students will be acquired, 120 males and 120 females. These students will range from different races, ethnicities, and socio-economic background. The participants will first be clustered based on gender, then subcategorized by social class, race, and where these participants originally reside. The clusters will allowRead MoreSona Research Proposal Paper1228 Words à |à 5 PagesProposed Methods Participants Approximately 168 participants, self-identifying female students from the University of Guelph in Guelph, Ontario will partake in this study. The participants will either volunteer to participate with the chance to win one $50 Stone road Mall gift card or to obtain credit towards their first-year psychology course. The participants will be asked to fill out a single online questionnaire that can be accessed from an electronic deceive (mobile device, desktop, laptop)Read MoreExploring The Potential For Addiction1543 Words à |à 7 Pagespilot study by Hussain and Griffiths (2009) set out to explore the potential for addiction to an MMORPG, within its psychological and psychosocial effects on players. Generally, studies of MMORPGs have not had a specific focus on addiction or the psychology of on-line gaming (as cited in Hussain Griffiths, 2009). At the time of their study, it was estimated that there were five million online gamers worldwide (as cited in Hussain Griffiths, 2009). According to the statistical analysis site StatistaRead MoreThe Distribution Of Watches962 Words à |à 4 Pageswill be distributed to participants after practice in the Survey Room. Communication with Participants A daily email reminder will be sent each evening to each participant reminding them of their schedule for the following day. At approximately 12:30 pm each day an email will be sent to the participant providing them with their participant number and a link to the pre-practice survey and a reminder to meet in the Survey Room to take the pre-practice survey. Participants will receive text messagesRead MoreA Brief Note On The International Personality Item Pool1139 Words à |à 5 PagesPersonality Item Pool, abbreviated IPIP, was originally conceptualized as a component of a project by Wim K. Hofstee at the University of Groningen in the Netherlands (International Personality Item Pool, n.d.). Hofstee and his fellow researchers sought to create items for personality based ââ¬Å"on short, concrete behavioral phrases [which] would be less subject to idiosyncratic interpretation than ratings on relatively abstract trait adjectivesâ⬠(International Personality Item Pool, n.d.). In threeRead MoreResearch Study On Video Games Essay779 Words à |à 4 PagesA. SeX-Box: Exposure to Sexist Video Games Predicts Benevolent Sexism B. S. Paul Stermer and Melissa Burkley, Oklahoma State University C. Psychology of Popular Media Culture 2015, Volume 4, No. 1, 47-55 D. This research study sought to determine if choosing to play video games for long periods of time that contained high values of sexist content is associated with projecting sexist attitudes. It was hypothesized that men, rather than women who played video games regularly with high sexist contentRead MoreCorrelation Between First And Secondary Psychopathy And Cognitive Empathy Essay1284 Words à |à 6 Pagesbased off our intel from Chamorro-Premuzic, 2010) that Primary Psychopathy and Empathy will be negatively correlated whereas Secondary Psychopathy and Empathy will be positively correlated . Our subject pool consisted of 452 participants, 113 male and 339 female, where they completed a questionnaire of 2-parts; each part determinant of either Psychopathy or Empathy. The scores were correlated against one another, finding an insignificant negative association for each relationship, hence partially supportingRead MoreHow Undergraduate College Women in the United States Perceive Ra pe and Sexual Assault671 Words à |à 3 Pageshook-ups or casual sex. Setting: A large southeastern university in the United States. Subjects: The subjects consisted of 109 female undergraduate students who were recruited from the psychology department participant pool. Women were between 18 and 46 years of age, with a mean age of 22.6 years. Participants were split between grade level with 6.4% freshman, 18.3% sophomores, 37.6% juniors, and 36.7% seniors. In terms of ethnicity the women were 54% European American, 19% Latina, 21% AfricanRead MoreThe Effects Of Facebook s Mood And Body Image Perception Essay1350 Words à |à 6 Pagesbody image concerns. Methods and procedures used by authors Conducted in United Kingdom, participants were recruited for a study on ââ¬Å"Media Use and Memoryâ⬠through the university psychology student participant pool and given course credit for their participation.â⬠It involved 112 female students and staff members aged between 17 and 25 years old. Participants average body mass index was 23.40. Among participants, 84 of them identified as white, 11 as Asian, 8 as black, 4 as mixed race, and 4 as ââ¬Å"otherâ⬠Read MoreIdentity and the Way Individuals Shape Their Identities for Themselves1341 Words à |à 6 PagesIdentity and the Way Individuals Shape Their Identities for Themselves One of the central issues of psychology is identity and the way individuals shape their identities for themselves. People live in different regions all around the globe and are consequently exposed to a distinct type of culture, religion, education, family values and media. These influences instill certain rigid values in people from birth, which configures their self-concept and the way they perceive other individuals
Wednesday, May 6, 2020
Evolution of the Immune System Free Essays
John Frelinger Dr. Travis Organic Evolution 30 April 2012 Evolution of the Immune System Animals are constantly bombarded by an immensely varied array of disease causing pathogens including bacteria, fungi, viruses and other parasites. The number of microbes living in the human body outnumber the actual human cells by a factor of 10, and for every single species of animal and plant on Earth, there are viruses that infect them. We will write a custom essay sample on Evolution of the Immune System or any similar topic only for you Order Now With the unrelenting threat of disease-causing pathogens all around us, and even within us, how can the constantly vulnerable organisms defend themselves? Evolution has provided an answer to this problemââ¬âthe immune system. The immune system is a vastly complex orchestra of cells working together to help eliminate potentially harmful pathogens from the body. Some form of host defense is found in every multicellular organism, however there are myriad variations in the immune systems of different organisms. Vertebrates have evolved an acquired immune response, in which a specific immune system is activated to clear an infection that is initially controlled by a non-specific (innate) immune response. This highly adaptable system is important to the survival of vertebrate species. Surprisingly, however, 90% of animals (invertebrates) do not have this kind of response. Despite lacking a seemingly critical adaptation, invertebrates continue to survive and reproduce. Why does it appear necessary for vertebrates to have an acquired response in order to survive, but the more numerous invertebrate species do not? Research indicates that there is an evolutionary lineage of the immune system that stems from the split of invertebrates and vertebrates. Innate immunity, which is found in all animals, is assumed to be at the beginning of this evolutionary tree. After the diversification of species (vertebrates branching from invertebrates), mechanisms of immunity also diverged. In this paper I will first discuss the function of the innate immune system because of its older evolutionary history, followed by the adaptive immune response that evolved later in vertebrate lineages. I will then conclude by placing the development of the innate and adaptive immune system in an evolutionary context. Innate immunity is the first line of defense for an organism and is made up of elements that protect the organism from pathogens. Anatomical aspects such as skin act as an impermeable barrier to infectious pathogens. Chemical and biological factors, including anti-microbial peptides like defensins, are also used to inhibit bacterial growth and prevent colonization. Another immunological factor of the innate immune system are phagocytic cells (macrophages), which are cells that engulf and eliminate foreign pathogens. These cells operate using a variety of different and generalized receptors that recognize a broad range of molecular patterns expressed by pathogens that initiate phagocytosis. One such family of receptors, known as Toll-like Receptors, recognizes common pathogen elements such as bacterial wall components or viral DNA sequences. This component is found in virtually every multicellular organism, ranging from sponges to humans (Muller and Muller 2003). Plants also express proteins that are very similar to toll-like receptors, indicating that this aspect of the innate immune system predates the divergence of plants and animals. The innate immune system is so valuable to an organismââ¬â¢s survival because it is always present and in many instances can prevent pathogen entry or replication. This, in turn, prevents a harmful infection from ever occurring inside the host. Although invertebrates do not have the acquired immune response, recent research has shown that their innate response is more complex than previously thought. Insects can activate their immune systems to remain in a higher state in order to prepare for a pathogen invasion. During bedbug mating, females are frequently injured in the process because males will stab a female to inject his sperm, infecting her with bacteria and exposing her to other potential infections. In response, females have evolved ways to enhance their immune system prior to mating in anticipation of pathogen invasion (Morrow and Arnqvist 2003). Bumblebees are capable of maintaining a heightened immune system in response to a prior pathogen invasion to aid in the prevention of future infections. Immunity such as this has been shown to pass down vertically to offspring, therefore increasing their fitness (Tyler et al. 006). Slugs have also evolved an interesting alternative response in the form of increased mutation rates of certain immune cell receptors, which allows their immune system to adapt to many foreign elements (Litman and Cooper 2007). While it is inherently different from the acquired immune response, this sensitive management of immune function was previously thought to be reserved as a characteristic of vertebrates and the adaptive immune response. As vertebrates began to diverge and evolve from invertebrates, so too did the immune system. The new adaptive branch of the immune system originally conferred a new selective advantage for vertebrates because of its specificity and immense flexibility in recognizing new pathogens. The clonal selection theory, in which each lymphocyte clonally expresses a specific antigen receptor, can help explain how the immune system can express an extremely wide range of potential receptors capable of recognizing new pathogens. Lymphocytes are undifferentiated cells that ultimately become B-cells (Bone Marrow) or T-cells (Thymus) depending on where they migrate. B-cells possess a uniquely structured immunoglobulin molecule (antibodies exposed on outer surface) that recognizes and binds to a specific molecular counterpart. When a foreign antigen is bound to the antibody, it stimulates the replication of that specific B-cell with the aid of Helper T-cells, which enhance B-cell maturation. This process results in the clonal expansion of cells that recognize the original antigen and subsequent production of antibodies that help in the eradication of the pathogen. An important point of this process is that the pathogens select which lymphocytes expand. It also results in memory B-cells and T-cells that constitute a persistent immune memory for a particular antigen. This expanded pool of memory cells is activated upon a second exposure to the same pathogen, resulting in a much more rapid immune response to clear infection. Other types of T-cells are also produced during this process. For example, cytotoxic T-cells target and kill virally infected cells, while suppressor or regulatory T-cells are activated when the infectious pathogens are eliminated and signal the immune system to subside. Cells such as these also experience selective pressuresââ¬âones that react to self-tissue (and harm the host) would be selected against, while those that recognize pathogens would survive and replicate. The clonal selection theory addresses many aspects of vertebrate immunity, however, it does not explain all of the mysteries behind the variety of antibody generation. The sheer number of antibodies that can be produced and the finding that the acquired immune response can generate antibodies to manmade molecules that are not present in nature led scientists to explore how such diversity is generated. Research done by Susumu Tonegawa in the 1970ââ¬â¢s indicated that B-cells have the ability to produce a huge number of antibodies due to a gene rearrangement process. B cells originally have many sets of gene segments (Variable, Diverse, and Joining) and over the course of its maturation reduce these segments to one of each type for the production of the antibody heavy chain. A similar process of gene rearrangement is involved for the production of the antibody light chain. The light chain and heavy chain proteins then assemble to form the complete antibody molecule that can specifically bind to an antigen. Two genes that are critical for this process to work are RAG1 and RAG2. These genes are known as recombination-activating genes and distinguish the vertebrate immune system from other lineages. These genes are critical to the process because they act as the excision and joining molecules that cut and knit back together the individual VDJ segments that make up the antibody. This results in the huge potential of diverse antibodies that can be producedââ¬âhundreds of millions of possible antibody types generated from a much smaller number of gene segments that can react with virtually any antigen. This sophisticated process may have originally been introduced by a mobile genetic element known as transposons. These transposable elements have the ability to excise themselves from one DNA sequence and incorporate themselves into another, very similar to the RAG1 and RAG2 gene functions. After the divergence of jawed and jawless vertebrates, a viral infection of the jawed lineageââ¬â¢s gametes may have introduced a transposon into their genome. (Thompson 1995). This may have provided the raw materials necessary to facilitate the development of adaptive immunity. The acquired response appears to have evolved from a single lineage because all vertebrates (excluding jawless fish) retain this RAG-mediated gene rearrangement system. The specificity of this kind of response may have been selected for because of its ability to recognize a diverse number of pathogens, but also because it could conserve more energy resources compared to the generalized defense of the innate response. The adaptive immune response is structured in such a way that it can respond to an almost infinite number of pathogens, while utilizing a relatively limited number of genes. Figure 1 illustrates a potential phylogeny based on some immune system adaptations previously discussed. Figure 1 (Reproduced from Litman and Cooper 2007). Although the vertebrate immune system is extremely adaptable to many potential threats, it is far from perfect. Epidemics such as the Bubonic Plague or the 1918 influenza killed millions of people. Similarly, when the Spanish colonized the New World, they also introduced pathogens that were devastating to the indigenous people. One of the major limitations of the acquired immune response is that it takes a relatively long time to respond after the initial exposure in order to be effective. This time is required because the lymphocytes must clonally expand before a pathogen can be eliminated. For example, in the case of the Native Americans, when they were exposed to the new pathogens, the infections spread to a portion of the population that was large enough to leave them unable to forage for food or to tend to the sick. As a result, it nearly wiped out the entire civilization. This limitation is significant as illustrated by these and many other historical epidemics. These difficulties have led scientists to think more fully about the effectiveness of the vertebrate immune system. If the immune system has the potential to combat virtually any conceivable threat, why then canââ¬â¢t it always eliminate any potentially harmful pathogen? We also look to immune hypersensitivity and autoimmunity as potential drawbacks of the immune system, indicating further imperfections of the adaptation. When the immune system mistakenly targets self-tissue, it results in serious consequences for the organism. Concepts in evolutionary biology might help address these issues. In this context the immune system does not have to be inherently perfect by design because only some individuals of a population need to survive and reproduce for that lineage to continue. The variation introduced by the immune system generates the diversity necessary for a population to adapt to changing environmental pressures. As others have suggested, a zebra doesnââ¬â¢t have to outrun the lion, just the slowest member of the herd (Hedrick 2004). The immune system is subjected to the same constraints as other characteristics in regards to natural selection. In this case even if a trait is not optimal, but helps the organism survive and reproduce, it will be selected for, regardless of any deleterious effects experienced post-reproduction. Many, but not all immunologists, believe the development of the adaptive immune system with gene rearrangement was a critical advance. It has been proposed that the development of the adaptive immune system was the ââ¬Å"Big Bangâ⬠for the evolution of immune system (Travis 2009). This development might have also enabled the rapid expansion of vertebrates. Moreover, the idea that the adaptive immune system can generate receptors for molecules that are not yet present, makes it extremely flexible and has been called ââ¬Å"forward thinkingâ⬠(Travis 2009). Thus, while the immune system does not anticipate every change in organisms it is ready for them by constructing a large repertoire of antigen specific receptors, which confers a big selective advantage. Others have suggested the adaptive immune system conserves resources, and thus is better than the innate system. In contrast, as noted earlier, invertebrates lack a fully functional adaptive immune system and are very successful. Moreover, others have argued that even if the immune system was an advantage, it was only temporary and short lived (Hedrick 2004). Another relevant issue deals with the concept of parasite and host co-evolution. This constant struggle is exemplified by a quote from Lewis Carrollââ¬â¢s ââ¬Å"Through the Looking Glassâ⬠, ââ¬Å"it takes all the running you can do, to keep in the same placeâ⬠. This concept, originally introduced by Leigh Van Valen, has been termed the Red Queen hypothesis. According to this hypothesis, an improvement in fitness for one species will lead to a selective advantage for that species. However, since species are often coevolving with one another, improvement in one species implies that it gains a competitive advantage over the other species, and thus has the potential to outcompete for shared resources. This means that fitness increase in one evolutionary system will tend to lead to fitness decrease in another system. The only way that a competing species can maintain its relative fitness is to improve on its own design. Although this theory was used to help explain the extinction of species and the evolution of sexual reproduction, it has been applied to many aspects of predator prey relationships including the development of the immune system. Because animals are constantly attacked by fast-adapting parasites, the host immune system cannot possibly gain an advantage over them. The evolution of the immune system is caused by the small advantages conferred as a result of variation in the recognition of pathogens. As suggested by Steven Hedrick, ââ¬Å"by selecting for more elusive parasites, the immune system is ultimately the cause of its own necessityâ⬠(Hedrick 2004). Thus paradoxically, the immune system, since it places a strong selective pressure on pathogens and parasites, ultimately has become essential for vertebrates to survive. By placing selective pressure on parasites that can evolve much more rapidly than animals (due to their higher reproductive/mutation rate), it results in parasites that are increasingly more effective at infecting hosts of that species. In terms of the immune system, one strategy that parasites have developed is a means of altering their own antigens to become unrecognizable. In this way they escape the adaptive immune system by altering their structure. For example, trypanosomes can switch the major target antigen for antibodies, which they use as a strategy to extend the amount of time they reside in the host. This results in a more contagious host that will increase the spread of pathogens to new hosts (Stockdale et al. 2008). Similarly, because the HIV polymerase is very error prone with no proof reading mechanism, many mutations arise in the HIV proteins during its infection. While the adaptive immune system can make neutralizing antibodies, new variants arise that can no longer be recognized by the antibodies. These new variants have a selective advantage and escape, and thus the adaptive immune systemà is always lagging behind. In terms of the host immune response, there is also an extremely high levelà of polymorphism of major histocompatibility genes, which enable the population to respond to a wider array of antigens using T-cells. The benefit of this heterozygosity is that it allows the individual to respond to a wider variety of antigens. Moreover this diversity helps ensure that even though some individuals may perish, the particular pathogen will not be able to eliminate the entire population. Some infectious agents have even taken it a step further and evolved ways to utilize the host immune system to increase their own fitness. For example, infections that result in pus filled cysts can be used to carry parasitic progeny and spread to new hosts when they burst. Even though this may help the host clear an infection, the pathogen can use this to increase its own fitness and infect more individuals. The Human Immunodeficiency Virus (HIV) utilizes the host immune system by initially infecting macrophages, and subsequently T-cells, which the virus uses as a reservoir for reproduction and as a means to spread to many different tissues in the body (Orenstein 2001). It also serves the virus to target immune cells for infection because crippling the host immune response akes it easier for the virus to spread throughout the body and eventually to new hosts (due to the higher viral load). In this light, it is possible that invertebrates did not evolve the adaptive immune response because they may have never needed it. By lacking the ability to develop a ââ¬Å"memoryâ⬠for a particular pathogen, those pathogens did not evolve anti-immune mechanisms to counter the host immune response. An immune memory could lead to more devious pathogens and resu lt in a more harmful infection in the future. This could have been a better strategy for invertebrates as it may have prevented the co-evolution of more virulent pathogens (Hedrick 2004). The immune system has a long evolutionary history in multicellular organisms. The innate immune system is a critical adaptation that helped these organisms survive the onslaught of parasites and pathogens. Vertebrates possess an adaptive immune response that allowed for the recognition of an almost infinite number of pathogenic antigens, however, it appears to have become a one-way road with the coevolution of pathogens. Once this adaptive system appeared in the vertebrate lineage, there was no going back. Because of the immense flexibility of the adaptive immune response, it places huge selective pressures on pathogens to constantly evolve new mechanisms of infecting hosts. Thus in the context of evolution, even with the incredible versatility of the adaptive immune system, it is likely there can not be an ultimate solution to infection by parasites only a new, perhaps unstable, equilibrium. Works Cited Hedrick, S. (2004). The Acquired Immune System: A Vantage from Beneath. Immunity 21, 607-615. Litman, G. and Cooper, M. (2007). Why Study the Evolution of Immunity? Nature Immunology 8, 547-548. Morrow, E. H. , and Arnqvist, G. (2003). Costly traumatic insemination and a female counter-adaptation in bed bugs. Proceedings of the Royal SocietyB: Biological Sciences. 270: 2377ââ¬â2381 Muller, W. and Muller, I. (2003). Origin of the Metazoan Immune System: Identification of the Molecules and Their Functions in Sponge. Integrative and Comparative Biology 43, 281-292. Orenstein, J. (2001). The Macrophage in HIV Infection. Immunobiol. 204, 598- 602. Stockdale, C. , Swiderski, M. , Barry D. , and Richard McCulloch (2008). Antigenic Variation in Trypanosoma brucei: Joining the DOTs. PLoS Biol 6. Thompson, C. B. (1995). New insights into V(D)J recombination and its role in the evolution of the immune system. Immunity 3, 531ââ¬â539. Travis, John. (2009). ââ¬Å"On the Origin of the Immune Systemâ⬠. Sciencemag Vol. 329. Tyler, E. , Adams, S. , and Mallon, E. (2006), An Immune Response in the Bumblebee,Bombus terrestris leads to increased food consumption. BMC Physiology 6. How to cite Evolution of the Immune System, Papers
Tuesday, May 5, 2020
The Impact of Financial Crisis 2007
Question: Describe about the impact of financial crisis 2007 on the financial management of health care industries? Answer: The financial conditions of the health care industries on the year of 2007: The financial condition of 2007, also called as the global economical crisis and 2007 economical crisis, this is measured by the economists to have been the most horrible economical crisis after the recession in the year of 1930. According to Warren,(2015) after the great depression of the global economy on the year of 1930 the world was experiencing the recession again. This recession impacted greatly on the finance condition of the hospitals greatly. More than a 50% of health financing drive the millions of people into the poverty. Major decrease in finance is due to the less hospitals are for the patients and decrease in the insurance policy for the employees and the unemployment of the people. This exposed the fall down of large health care organizations, and the stock market was still dropped worldwide. The financial crisis begins in the August 2007 in health care industries. There was a significant slowdown in health cost was an outcome of wider financial factors in this year o f 2007 (John, 2013). The structural changes in the health care system that had lead to slower growth as well. The main root of the crisis has started from the year of 2000 as stated by Tuffs, 2007. The inflation starts to increase despite the effort from the regulatory authorities and the central banks. The prices begin to fall and the loans started to be bad (Vithessonthi Tongurai, 2015). There was a severe sock in the finance of the health care industries. There are some cases of financial fraud had noticed in the year 2007. The most of the financial fraud has been done because some dishonest health cares providers. The most common types of fraud includes the billing for the health care services that never rendered, billing for most costly services, Wrongly diagnose patients for tests, surgeries etc. Also this includes accepting kickbacks for patient referrals. This had main insinuations for strategy, as health expenditure growth is a key driver of federal and state financial pla n throughout the Medicare plan. The financial impact of the ailment related malnutrition at the hospital admission had been noted. The frequency of the disease related mal nutrition for the patients admission to the hospitals had been calculated to be very high. The changes in the economy had impacted greatly in the development of the hospitals. The financial conditions of the health care industries on the year of 2012: The health care industries were going through recession since the year 2007 to 2011. As per Sheel, (2008) the global economy was also under a high decline. The decrease in the global finance impacted greatly to the development and financial structure of the hospitals. After the year 2011 and in the year of 2012 the global economy was increasing slowly that also resulted in the increase in the financial condition of the hospitals. Between the years 2007 to 2011 the financial condition of the healthcare industries considerably low due to sluggish economic recovery and continual increase in the price of the price sharing devices for privately insured, slow growth of the people programs. The above factors go ahead to projected expansion rates of close to 4percent throughout 2012. Over the year of 2012 period, national health spending is projected to grow at an average annual rate of 5.8percent. There was noticed a slowdown in the health spending due to the recession in the years 2007 to 2012 that had been noticed to be slightly increased in the year 2012. As a result of the slowdown there was a decline in the growth of the hospitals. There was a strong statically connection between recession and national health care spending noted in this year 2012 (Shortt, 2014). The outcome of financial activity on the health price and consumption is measured and extremely lagged. The health spending growth charge in progress to drop earlier than the vast recession but there was a remarkable progress in the health spending and financial condition of the hospitals. The key management shifts between the year 2007 to 2012: The key financial management shifts were there was a low rise in the financial condition of the healthcare industries as compared to the year of 2007 (Krueger Kuziemko, 2013). It has been noticed by the researchers that there was a steady increase in the health care spending since the year of 1930 although the rate of increase is very slow between the years 2007 to 2011. In the instant consequences of the economical crisis palliative economic and monetary plans were accepted to weaken the distress to the financial condition (NPR.org, 2007). It had been observed that the slowdown in the economy of the hospitals had been due to the extensive failures in the regulation of the hospital finances that also includes the Federal Reserves breakdown to stalk the wave of deadly mortgages. Roehrig, (2012) has mentioned that after the year of 2011 there is a noticeable increase in the rise in the economy of the world. That had impacted greatly on the increase of financial condition of the health care organization. The changes occurred: The changes occurred due to the changes in the global economy and that effect the health industry too. The changes that occurred to the health care industries are the increase in the health spending by the people. Increase in employment also increases the policies for health care insurances (Karanikolos et al, 2013). The people who are insured had a financial defensive effect in defensive people as of the full price of care for their health. Customers can perceive health care as a necessity that is different from other economic supplies. The companies cannot make instant changes in the benefits of the health care. The health care organizations were very much deliberate in their decision regarding whether to increase or pact services and wealth expenditures. As stated by Kondilis et al. (2013). The legislated vary in expenditure beneath Medicaid with Medicare might require an extensive process of discuss before any considerable alterations are completed. In detail, as joblessness incr eases and incomes go down, Medicaid expenses have a tendency to rise up as much people turn into qualified for the plan, while affirms in reaction may respond by cutting the eligibility or expenditures to the suppliers (Schneider et al. 2015). From an analysis it has been noticed that the decrease in health expenditures growth in the years what was occurrence more generally in the financial system. The slowdown in the financial management was may be due to the slowdown in the health spending by the people. The emerging changes: There was an increase in the financial condition of the health care organizations since the recession age of 2007 to 2012. As the financial condition recovering slowly the health spending is also at a rise. Although growth taxes are improbable to go back to the two digit levels that were in the past years (Frayss, 2015). The increase in the future healths spending also depend on whether the extra health expenses stay at the comparatively self-effacing level of current years or return to the past standard. It has been shown from the past that earlier hard work to control the costs of the health care had only ashort time effect, and there were initial signs that the recessions or slowdown (self-determining of the belongings of the financial state) is beginning to wane (Hall, 2015). Changes in the affordable care act can also affect financial condition of the health care industry. Rise in treatment will encourage a unassuming, one-time bang of a pair percent in expenditure as public who are earlier were not insured acquire insurance and improved entrance to health care services. As mentioned by Schaumburg, 2013, this was proved to match through a predictable financial recovery, so an increased rate of growth in health expenditure because of facilitate recovery must not be accredited to the affordable care act just because of the concurrent timing. Positive changes for long term economic growth, why and why not: Yes the rise in the economy has always a positive effect on the long term financial management of the health care organizations as stated by Fairlie, 2013. Since the increase in the economy may increase the rate of employment and financial condition of people. So there is a better chance of rice in economy of the hospitals and health care organizations. The rise in global economy will develop new organizations and firms. The employers may opt for some medical policies for the employees so there is a chance of growth in the financial condition of the health care organizations. As per Fox, (2013) there is also a chance of fall in to the recession that can fall the global economy. This may also decrease the health spending of the employees and the public which could lead to the decrease in the financial condition of the hospitals. These changes are may be increase the increase the financial level of the hospitals but there is not any long term improvement in the financial management of the health care organizations. As per the perception from the policy considerate example of health expenditure in the past is first and foremost of importance as a conduct for that occur in the near future. References list: Fairlie, R. (2013). Entrepreneurship, Economic Conditions, and the Great Recession. Journal Of Economics Management Strategy, 22(2), 207-231. doi:10.1111/jems.12017 Fox, D. (2013). Health inequality and governance in Scotland since 2007. Public Health, 127(6), 503-513. doi:10.1016/j.puhe.2013.04.019 Frayss, O. (2015). La grande rcession amricaine de 2007, les retraites et le rve amricain. Ideas, (5). doi:10.4000/ideas.947 Hall, S. (2015). Everyday family experiences of the financial crisis: getting by in the recent economic recession. 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